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Dissecting the Biological Motherboard (Systems Biology and Beyond) Nature Precedings
Abhay Krishna; Ajit Narayanan.
Genome-scale molecular networks, including gene pathways, gene regulatory networks and protein interactions, are central to the investigation of the nascent disciplines of systems biology and bio-complexity. Dissecting these genome-scale molecular networks in its all-possible manifestations is paramount in our quest for a genotype-input phenotype-output application which will also take environment-genome interactions into account.

Machine learning approaches are now increasingly being used for reverse engineering such networks. Our work stresses the importance of a system approach in biological research and how artificial neural networks are at the forefront of Artificial Intelligence techniques that are increasingly...
Tipo: Presentation Palavras-chave: Ecology; Bioinformatics.
Ano: 2008 URL: http://precedings.nature.com/documents/2003/version/1
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Ecoinformatics: where are we, where do we want to go, and how to reach there. Nature Precedings
Abhay Krishna.
Compared to other natural sciences ecological sciences has always been about seeing the bigger picture. The realization that local actions can have global impact has been the hallmark of ecological research. This integrative view is getting more and more accepted now with the recognition that whole is definitely more then sum of its parts. Advancement in computer sciences has now made it possible to comprehend the complexity arising from an integrative approach. This has given rise to a field interfacing computer science and ecological sciences called Ecoinformatics. The other popular parallel and more mature field is bioinformatics or computational biology. The presentation will take the audience on an Ecoinformatics tour touching on present status of...
Tipo: Presentation Palavras-chave: Ecology; Bioinformatics; Earth & Environment.
Ano: 2008 URL: http://precedings.nature.com/documents/2018/version/1
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Web 2.0 and the ever elusive balance between information explosion and data mining Nature Precedings
Abhay Krishna.
In a fascinating tussle of perspectives in Volume 6 and issue no 3 of april 2008 Frontiers in Ecology and Evolution, Martin A Nuñez and Gregory M Crustinger enlist ways to brace up with the recent literature. They advocate that PhD students should choose a well studied system to have better chances of success. On the other side of this fascinating tussle Daniel Simberloff and Nathan J Sanders agree with there enthusiastic case and approaches for bracing up with the recent literature. However, they disagree with the play safe strategy of start-ups in ecology and evolution.

For me this tussle of perspectives is really fascinating. It underlines the story of our times. In the times of information explosion, should...
Tipo: Manuscript Palavras-chave: Ecology; Bioinformatics; Earth & Environment.
Ano: 2008 URL: http://precedings.nature.com/documents/1959/version/1
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